Among 200 hits, three genes (DEDD, ABCB10, and UAP1) are dysregulated (amplification and messenger RNA (mRNA) upregulation) in more than 40% of TNBC tumors (Fig. 1c) and in 20% of all breast tumors examined (Supplementary Fig. 2B, C). This evidence concerns the gene UAP1 and breast neoplasm.