To define the extent to which the correlation between SETD1A expression and these cellular processes is relevant in clinical samples, we analyzed single-cell RNA-Sequencing data derived from primary patient-derived circulating tumor cells (CTCs) enriched from women with advanced breast cancer29,30, which also confirmed the correlation in expression between SETD1A and genes involved in mitosis and DNA damage repair (Fig. 3d). This evidence concerns the gene SETD1A and neoplasm.