Out of the 233 reported candidate IBD-risk genes, 40 genes presented very low or undetectable counts in the mouse data set (i.e., IL23R, SULT1A2, ERAP2, and MUC19), 118 were detected but did not have their expression altered through the development of inflammation (i.e., TNFRSF14, ATG16L1, GPR35, and TNFSF8), and 75 were found among the DEGs in our mouse data set (Supplementary Fig. 5a and Supplementary Data set 6). Here, IL23R is linked to inflammatory bowel disease.