Durvalumab, an anti-PD-L1 antibody, has significantly prolonged PFS by more than twofold compared with the placebo (17.2 v 5.6 months, HR = 0.51) among patients with unresectable stage III NSCLC without disease progression after concurrent chemoradiotherapy in PACIFIC [65]. The gene discussed is CD274; the disease is non-small cell lung carcinoma.