Studies using qPCR [135,136], but not those using RNA sequencing (RNAseq), reported a significant increase in the expression levels of all these four mRNAs (VEGFA mRNA, CCL2 mRNA, KIF5C mRNA, and DCTN1 mRNA) in the PBMCs from ALS patients. The gene discussed is VEGFA; the disease is amyotrophic lateral sclerosis.