Further analysis revealed the significant elevation of SOCS3 levels in each allergic sub-group; asthma (mean fold change = 5.97 ± 0.3, p–value = <0.0001), rhinitis (mean fold change = 5.46 ± 0.25, p–value = <0.0001), dermatitis (mean fold change = 14.7 ± 0.3, p–value = <0.0001), conjunctivitis (mean fold change = 5.97 ± 0.2, p–value = <0.0001) and food allergy (mean fold change = 2.3 ± 0.1, p–value = <0.0001). Here, SOCS3 is linked to skin disorder.