Previous studies have reported that STAT signalling plays an important role in the regulation of the intestinal mucosal immune response and intestinal epithelial cell apoptosis.17, 37 We wanted to assess the effect of Bry‐1 on STAT signalling, as this information may provide a molecular explanation for the role of Bry‐1 in protecting against colitis. This evidence concerns the gene SOAT1 and colitis.