GBA1 and Cognitive impairment: Progression to mild cognitive impairment was worse among the combined GBA1 group (OR, 4.2; 95% CI: 1.1–16.6; P < 0.05), heterozygous (OR, 2.6; 95% CI: 1.6–11.4; P < 0.05), and biallelic group (OR, 8.2; 95% CI: 1.6–41.0; P < 0.05; Fig.1).