However, considering the long‐term inhibition/activation efficiency and the cytotoxicity of autophagy inhibitors and AMPK inhibitors on tumor cells and their side effects on tumor‐bearing animals, our in vivo studies did not apply these chemicals on animals.23, 24 In the future, LKB1 or AMPK genetically knockdown or knockout animals may be used to detect whether LKB1/AMPK is essential for JQ1 to induce autophagy and inhibitory BC cell proliferation in vivo, though whether the knockdown/knockout may directly change cell proliferation is still a concern. This evidence concerns the gene STK11 and neoplasm.