CD8A and HIV infectious disease: However, these findings are biologically consistent with our IL‐6 results and suggest that variable ART adherence may be most impactful through a unified inflammatory pathway that involves these biomarkers (and could possibly also include CRP), in comparison to other networks of inflammation or defective adaptive immunity (i.e. CD4+/CD8+T‐cell ratio) that are associated with adverse outcomes in HIV infection 34, 37.