KIRC (kidney renal clear cell carcinoma) is the most common type of renal cell carcinoma, accounting for 70%‐80% of all renal cell carcinoma cases.27 KIRP (kidney renal papillary cell carcinoma) is the second most common histological subtype of RCC (renal cell carcinoma), and it accounts for 10% to 15% of all RCCs.28 The results of survival analysis illustrated that KIRC and KIRP patients expressing high levels of BIRC5 presented a significantly poorer prognosis than those expressing low levels of BIRC5 (Figure 1C,D). Here, BIRC5 is linked to hereditary clear cell renal cell carcinoma.