Among other animal models, the mutant mouse Disrupted-in schizophrenia 1 (human full length DISC1 overexpression) gene has shown to lead to neurodevelopmental changes consistent with the proposed neurodevelopmental origin of schizophrenia, i.e., reduction of PV INs in cortex and striatum and impaired migration of INs from ganglionic eminence [141, 142]. Here, DISC1 is linked to schizophrenia.