In a meta-analysis of 54 long-term prospective studies including 160,309 subjects without previous vascular disease, the risk ratio per 1 SD increase in CRP was 1.37 for coronary heart disease, and 1.27 for ischemic stroke.17Accordingly, we found an association between hs-CRP and both MI and ischemic stroke in our study. The gene discussed is CRP; the disease is myocardial infarction.