Among the studies reporting inherited coagulation disorders in MINOCA, Van de Water et al12demonstrated that MINOCA patients younger than 50 years are more likely to express either FVL or PGM compared with patients older than 50 years (20 vs. 6%,p < 0.05), whereas the mean age of our MINOCA group was 58 (range: 18–87). Here, F5 is linked to blood coagulation disease.