Mechanistically, a rise in the number of CD62E+ PS+ MVs is plausible as increased plasma levels of TG have been shown to cause endothelial activation39, 40and MVs can be released in response to cell activation.41Ferreira et al reported that postprandial hypertriglyceridemia induced elevated levels of endothelium-derived MVs both in the early (1 hour) postprandial phase and 3 hours after food intake. The gene discussed is SELE; the disease is hypertriglyceridemia.