FPS inhibits thrombin generation independent of activated protein C by potentiating TFPI's activity.28Increased DDs have also been reported to have an in vitro effect of prolonging lag time in patients with acute myocardial infarction.29DDs were higher in our morbidly obese group and this may be additional contributor to the prolonged lag time observed. This evidence concerns the gene TFPI and myocardial infarction.