Wet AMD and DR are serious public health problems because it could lead to blindness if not treated properly.26, 27 Posterior eye diseases are the leading causes of blindness in developed countries.28 The invention of anti‐VEGF therapy and the success of clinical use were encouraging; however, the once‐per‐month injection scheme for the management of chronic eye diseases was impossible to be implemented in most parts of the world. The gene discussed is VEGFA; the disease is age-related macular degeneration.