DICER1 and pleuropulmonary blastoma: Factors favoring the diagnosis of PPB include some specific features such as the development of pneumothorax, the evidence of bilateral or multisegment involvement and of a complex cyst, and, finally, a germline mutation in the DICER1 gene, whereas CPAM is more likely with prenatal diagnosis, and the presence of a systemic feeding vessel and hyperinflated lung (24).