As shown in Fig. 5, the higher expression of COL6A3 (HR = 1.32, 95% CI [1.11–1.58], p = 0.0018), SERPINH1 (HR = 1.97, 95% CI [1.61–2.41], p = 3.1e−11) and PLEKHG1 (HR = 1.34, 95% CI [1.07–1.69], p = 0.012) were all significantly correlated with poor OS in GC. The gene discussed is COL6A3; the disease is gastric cancer.