CCL5 and acrocephalopolysyndactyly: As for chemokines, RANTES known to attract eosinophils [19, 20] and M-CSF often appears in the context of recruitment, activation, and survival of eosinophils [20, 21], both of which were not upregulated in ACPs compared with control, further supporting the hypothesis that allergy could have a poor role in the pathogenesis of ACPs.