To verify the induction effects of NPC exosomes on MSC differentiation into NP-like cells, Western blot and qRT-PCR were performed to detect the expression of collagen II, aggrecan, and Sox9 in MSCs after being incubated with NPC exosomes in 7, 14, and 21 days. The gene discussed is ACAN; the disease is nasopharyngeal carcinoma.