SELL and neoplasm: When parental B16F10 cells are transplanted into CD62Lwt mice, tumor growth was not significantly different than in the background C57BL/6 (B6) strain (Figure 2A), indicating that abrogating gene silencing of L-selectin on its own does not boost anti-tumor immunity over and above that seen in wildtype B6 mice expressing endogenous L-selectin.