To determine whether this effect was due to the action of enhanced expression of L-selectin on antigen-specific T cells, CD8+ T cells from transgenic mice homozygous for both the F5 TCR and CD62LΔP (F5LΔP) were transferred into C57BL/6 mice with established NP68-B16 melanomas (Figure 2B). This evidence concerns the gene SELL and melanoma.