FCGR2A [131R/H] is considered to be a heritable risk factor for a variety of infectious and inflammatory autoimmune diseases, including systemic lupus erythematosus, rheumatoid arthritis, malaria, multiple sclerosis, and anti-neutrophil cytoplasmic auto-antibody positive systemic vasculitis (65). The gene discussed is FCGR2A; the disease is rheumatoid arthritis.