In a previous publication, we analysed almost the same patients enrolled in the current study (n = 88) and focused on the roles of GSTM1, GSTT1, GSTP1, and other genetic polymorphisms in genes involved in the repair of DNA damage induced by CDDP and apoptosis of cells with CDDP-induced lesions, only in severity of vomiting presented by HNSCC patients treated with CDDP chemoradiation14. Here, GSTP1 is linked to head and neck squamous cell carcinoma.