CSF levels of ATG-5 were increased in Gd+ MS (mean ± SD 42.10 ± 11.22 ng/ml) with respect to Gd− MS subjects (mean ± SD 14.93 ± 6.54 ng/ml) (unpaired t test; p < 0.0001) (Fig. 2b). This evidence concerns the gene ATG5 and myeloid sarcoma.