CSF levels of Parkin were greater in Gd+ MS (median, IQR 34.08, 29.02–42.56 pg/ml) than in Gd− MS subjects (median, IQR 11.34, 9.55–15.32 pg/ml) (Mann-Whitney; p < 0.0001) (Fig. 2d). The gene discussed is PRKN; the disease is myeloid sarcoma.