CDH11 and neoplasm: The tumor burden curve representing the change in the bioluminescence over time demonstrated that the tumor burden in the anti-CDH11 group was significantly lower with 37.1, 30.6, and 57.7% lesser tumor bioluminescence intensity in the anti-CDH11 mice by week 2, 4, and 6 or treatment, respectively, compared to the control mice (p < 0.05) (Fig. 5b).