CAT and Decreased liver function: Both groups with cisplatin-induced toxicity, i.e., prophylactic control and curative control groups, showed a significant increase of serum alanine transaminase (ALT), serum aspartate aminotransferase (AST), tissue malondialdehyde (MDA), and a decrease of tissue catalase (CAT) levels as compared to the normal control group at p < 0.05, depicting marked induction of liver dysfunction.