It was reported by Qiu et al. that triptolide, a diterpene triepoxide, of a medicinal plant called Tripterygium regelii, which is effective against inflammatory diseases including rheumatoid arthritis, systemic lupus erythematosus, and atopic dermatitis (atopic eczema) [34], suppressed IL-2 production by TCR-stimulated T cells by inhibiting the activation of some transcription factors, such as NF-κB and NF-AT [20]. Here, NFKB1 is linked to atopic eczema.