We found that maternal HF diet was associated with reduced mRNA expression of Paneth cell AMP Reg3g, which targets Gram-positive bacteria [62], no change in mRNA expression of AMPs Lyz1 and Lyz2, and less low-intensity Lyz staining, which may suggest an overall greater production of Lyz protein, which can target both Gram-positive and Gram-negative bacteria [63]. Here, LYZ is linked to hydrops fetalis.