TNFSF10 and colonic neoplasm: To examine the sensitivity of colon cancer cells to TRAIL, HCT116, and HCT15 cells were treated with increasing concentrations of rhTRAIL alone or in combination with sunitinib for 24 h and cell viability was assessed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay (Figure 1A).