It has been demonstrated that treatment of prostate cancer cells with green tea polyphenols (GTPs) reversed the DNA hypermethylation-mediated silencing of the known tumor suppressor gene glutathione-S-transferase pi (GSTP1) through the downregulation of DNMT1, MeCP2, and several other MBD proteins (113). Here, MECP2 is linked to prostate carcinoma.