The upper panel of Figure 2B shows the detection of LRIG3 in whole-cell lysates of glioma cell lines transduced with inducible pLVX-TRE3G-LRIG3 expression vector, with or without the addition of Dox, while the lower panel shows the detection of sLRIG3 in the corresponding concentrated culture supernatants. The gene discussed is LRIG3; the disease is glioma.