CD8A and Zika virus infectious disease: Our study using a sequential model of DENV2 followed by ZIKV infection in Ifnar1−/− HLA transgenic B*0702 and A*0101 mice showed that DENV2-elicited CD8+ T cells recognized epitopes in ZIKV NS proteins, of which ~40% were located in NS3 and ~20% each in NS2A, NS4B, and NS5 (37).