Anti-PD-L1 based therapy, specifically atezolizumab, is now a standard of care option in combination with the chemotherapy drug nab-paclitaxel for TNBC that have at least 1% PD-L1 expressing tumor infiltrating immune cells, based on the results of the Impassion 130 clinical trial, which demonstrated a 10-month improvement in overall survival for the combination (73). Here, CD274 is linked to neoplasm.