Accordingly, DH patients may show asymptomatic IgA immune complex deposition in the kidney (106); Preisz et al. described deposits of eTG/IgA1 complexes in both upper and deep dermal vessels in roughly 64% of DH patients (107); rare clinical manifestations of DH include digital purpura and ecchymosis, that show evidence of small vessels vasculitis on microscopic examination (49, 108); circulating eTG/IgA immune complexes can be found in patients with DH and their concentrations decrease under the GFD (109). Here, IGHA1 is linked to dermatitis herpetiformis, familial.