IL10 and dermatitis herpetiformis, familial: In another study, our group demonstrated that, in DH skin, Tregs and IL-10 were significantly reduced compared to the skin of healthy subjects, whereas both coeliac and DH patients had a similar number of Tregs in duodenal biopsies, suggesting that the down-regulation of Tregs in the skin may be critical for the development of DH lesions (93).