➣ Primary tumor expansion rate ↓ (96, 396, 400, 401)IFN-γ (401)Retained in perforin KO mice (401)➣ Metastasis formation ↓ (394, 401)Tumor CD73 (394)NK cells > CD8+ T cells (394)➣ Survival ↑ (394, 396, 401)CD8+ T cells > NK cells (394). This evidence concerns the gene PRF1 and neoplasm.