Eventually, a core module with 13 genes including CEACAM6, CYP4B1, EIF2S2, HID1, IFFO1,MYO18A, PDCD2, SGIP1, SWSAP1, and 4 unknown genes (A_24_P127621, A_24_P255786, A_24_P683553, A_24_P916979) were identified and in silico validated in association with the indicator of invasiveness and prognosis of PA, plus some related cancer types. The gene discussed is PDCD2; the disease is cancer.