Due to the low frequency of TPMT alleles in East Asian population, 97.5% (n = 238) of all ALL patients were classified into wild type (GVBTPMT = 1.00 ± 0.00) and only six (2.50%) were classified into variant type (GVBTPMT = 0.10 ± 0.00) groups, resulting in poor statistical significance (p = 0.408 by T-test, p = 0.272 (ρ = 0.07) by Spearman’s rank correlation, p = 0.271 (τ = 0.06) by Kendall’s rank correlation) (Figure 3B). This evidence concerns the gene TPMT and acute lymphoblastic leukemia.