FGFR3 and Balkan nephropathy: It has been speculated that FGFR3, Akt, mucin type O-glycan biosynthesis, ECM receptor interaction pathways, and other biological mechanisms might be involved in the occurrences of AAN, BEN, and/or AA-induced UTUC (Tao et al., 2015; Lv et al., 2016; Popovska-Jankovic et al., 2016).