VEGFA and renal fibrosis: Kandasamy and Ashokkumar (Kandasamy and Ashokkumar, 2014) suggested that Myr could attenuate rat renal fibrosis induced by STZ combined with cadmium, and the underlying mechanism might be associated with downregulation of the expression of sterol regulatory element binding proteins (Kandasamy and Ashokkumar, 2014), which induce the expression of TGF-β and vascular endothelial growth factor, and result in renal fibrosis (Kandasamy and Ashokkumar, 2014).