CD38 and myeloid sarcoma: Herrmann et al. (2016) also demonstrated in their report that Sphingosine 1-phosphate (S1P)-receptor modulator FTY720 (fingolimod), which is the first oral therapeutic agent for MS and exerts its function, at least in part, by inhibiting lymphocyte trafficking from secondary lymphoid organs, effectively suppressed EAE severity and reduced the level of CD38 expression in the lymph nodes.