Additionally, we validated this concept by showing that in disease models of neurodegeneration (glaucoma causing RGC neuronal death (Bai et al., 2010b) and a genetically driven model of RP causing photoreceptor neuronal death (Galán et al., 2017b), reduced TrkC.T1 expression had significantly reduced disease progression. This evidence concerns the gene NTRK3 and glaucoma.