TMPRSS4 is a member of TTPs and is often overexpressed in many types of cancer tissues such as pancreatic, thyroid, colon, lung, gastric, breast and other cancer tissues, with a poor clinical prognostic (Kim et al.,2014; Chikaishi et al., 2016; Wu et al., 2014; Liang et al., 2013; Cheng et al., 2013). This evidence concerns the gene TMPRSS4 and cancer.