CXCL8 and colorectal carcinoma: In contradictory to the present study, Landi et al., (2003) in Spanish population, Theorodopolous et al., (2006) in Greek population and Dumitrescu et al., (2012) in Romanian population reported that, the IL-8 -251 T>A genotypes was not associated with a higher risk for CRC predisposition.