TNF and colorectal carcinoma: Few other earlier studies (Theodoropoulos et al., 2006; Ohtani et al., 2009; Theodoratou et al., 2012; Guo et al., 2013; Stanilov et al., 2014) and two earlier meta- analyses (Wang et al., 2011; Chen et al., 2013) also reported no association of TNF-α -308 G>A polymorphism with CRC risk.