CXCL8 and colorectal carcinoma: The homozygous variant genotype AA of IL-8 was associated with higher risk for CRC development in both age groups – for individuals in the more than 50 years age group (OR 3.733, 95% CI 1.276-10.919, p=0.016) as well as those in less than 50 years age group (OR 8.095, 95% CI 2.209-29.660, p=0.002).