HSPA5 and colorectal carcinoma: No correlation was observed between GRP78 expression level (Fig. 3e, left panel) and the IC50 for 5-FU (Fig. 3c) and CPT-11 (Fig. 3d) in the CRC cells (5-FU: HT29, 373.31 ± 61.44 μM; CCL227, 123.19 ± 19.85 μM; HCT116, 73.02 ± 15.20 μM.