At the present time, no intervention study has been published that examines whether consuming reduced GI or GL foods can reduce incident T2D as an endpoint. However, intervention studies in both Caucasian and Asian populations have been conducted using alpha-glucosidase inhibitors of intestinal starch and sucrose digestion (e.g., Acarbose) to slow (rather than prevent) carbohydrate digestion and lower the glycemic response to diet, thereby lowering dietary GI and GL [50,51,52]. The gene discussed is GAA; the disease is type 2 diabetes mellitus.