In that study, although association between FGFR2 expression and survival outcomes in patients with stage II/III GC after surgery and S-1 chemotherapy was insignificant, patients with recurrence after five years of treatment made up a relatively large proportion of the high FGFR2 levels, implying the FGFR2 overexpression may be relevant to GC development [77]. This evidence concerns the gene FGFR2 and gastric cancer.