APOC1 and hyperinsulinemic hypoglycemia, familial, 4: Levels of serum APOC1, which were similarly affected by CBS deficiency and ischemic stroke subtypes, and levels APOC3, which were affected only by CBS deficiency in the present study (Table 3), were also reported to be similar between ischemic stroke and controls but significantly different between hemorrhagic stroke and controls in another study [29].