To provide further evidence for the AMPK-dependence of the observed increase in GPER1 expression upon D-glucose deprivation, experiments to determine if GPER1 expression is sensitive to [D-glucose] in two Eker rat uterine leiomyoma cell lines (ELT-3 and ELT-6) were performed. This evidence concerns the gene GPER1 and uterine corpus leiomyoma.