DCLK3 and infection: The CLR KO mice with highest susceptibility (Dectin-1-Dectin-2 DKO and Mincle-Dectin-2-Dectin-1 TKO1) to systemic infection with C. albicans (Fig 1A and 1B) displayed the highest fungal burden in the kidneys and brains with low dose infection 6–7 days post-infection (Fig 1C and 1D).